Protected areas (PAs) are globally important environmental management tools against the effects of human activities, as they support the conservation of marine biodiversity, habitats, ecosystems and the processes within them, as well as resources Conditioner in a broad sense.However, the application of Ecosystem Services (ESs) research in the envir

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, has given rise to many new variants with increased transmissibility and the ability to evade vaccine protection.The 78-kDa glucose-regulated protein (GRP78) is a major endoplasmic reticulum (ER) chaperone that has aquarium cleaning suppli

Trichomoniasis is a public health problem worldwide.Trichomoniasis treatment consists of the use of nitroimidazole derivatives; however, Liquid Foundation therapeutic ineffectiveness occurs in 5 to 20 % of the cases.Therefore, it is essential to propose new pharmacological agents against this disease.In this work, esters of quinoxaline-7-carboxylat

Abstract Despite the proven success of hormonal therapy for prostate cancer using chemical or surgical castration, most patients eventually will progress to a phase of the disease that is metastatic and shows resistance to further hormonal manipulation.This has been termed metastatic castrate-resistant prostate cancer (mCRPC).Despite this designati